Do you notice anything different about me?
These are seriously the scariest words a guy can hear come out of a woman's mouth. The reason at that moment we need to go back into our archive of what this woman looked like in the past and then identify what has changed. Then we need to express that any and all changes are an improvement over the former state of the what ever it was.

Guy Tip: Take the offensive, when you are talking to a lady friend, ask them "Do you notice anything different?" Even if nothing has changed.